Ginkgo

Common name

ginkgo, Ginkgo biloba, fossil tree, maidenhair tree, Japanese silver apricot, baiguo, yinhsing

ID

HD0156

Scientific name of the plant

Ginkgo biloba

Anatomical part for use

leaf

Human use

Circulatory disorders

Summary

Ginkgo is a genus of highly unusual non-flowering seed plants. The scientific name is also used as the English name. The order to which it belongs, Ginkgoales, first appeared in the Permian, 270 million years ago, and is now the only living genus within the order. The rate of evolution within the genus has been slow, and almost all its species had become extinct by the end of the Pliocene; the exception is the sole living species, Ginkgo biloba, which is only found in the wild in China, but is cultivated across the world. The relationships between ginkgos and other groups of plants are not fully resolved. (Source: Wiki)

Evidence Level

Level 0 (No convinced report of liver injury caused by herbal and dietary supplement)

Hepatotoxicity Description

Despite wide spread use, ginkgo has not been specifically linked to liver injury, either in the form of transient serum enzyme elevations or clinically apparent acute liver injury. Indeed, ginkgo is sometimes used to treat acute or chronic liver injury. Gingko demostrates some degree of inhibition of cytochrome P450 activity in vitro, but in doses used in humans it appears to have little effect on drug metabolism. Several instances of excessive bleeding during therapy with ginkgo have been attributed to drug interactions with antiplatelet medications or anticoagulants. (Source: LiverTox)