L-tryptophan
Common name
N/A
ID
HD0193
Scientific name of the plant
N/A
Anatomical part for use
N/A
Human use
Sleep disorders & temporary insomnia
Summary
Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a non-polar aromatic amino acid. It is essential in humans, meaning that the body cannot synthesize it and it must be obtained from the diet. Tryptophan is also a precursor to the neurotransmitter serotonin, the hormone melatonin, and vitamin B3. It is encoded by the codon UGG.
Like other amino acids, tryptophan is a zwitterion at physiological pH where the amino group is protonated (–NH+3; pKa = 9.39) and the carboxylic acid is deprotonated ( –COO−; pKa = 2.38).
Evidence Level
Level 0 (No convinced report of liver injury caused by herbal and dietary supplement)
Hepatotoxicity Description
N/A
Common name
N/A
ID
HD0193
Scientific name of the plant
N/A
Anatomical part for use
N/A
Human use
Sleep disorders & temporary insomnia
Summary
Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a non-polar aromatic amino acid. It is essential in humans, meaning that the body cannot synthesize it and it must be obtained from the diet. Tryptophan is also a precursor to the neurotransmitter serotonin, the hormone melatonin, and vitamin B3. It is encoded by the codon UGG. Like other amino acids, tryptophan is a zwitterion at physiological pH where the amino group is protonated (–NH+3; pKa = 9.39) and the carboxylic acid is deprotonated ( –COO−; pKa = 2.38).
Evidence Level
Level 0 (No convinced report of liver injury caused by herbal and dietary supplement)
Hepatotoxicity Description
N/A