Yohimbe

Common name

johimbe

ID

HD0295

Scientific name of the plant

Pausinystalia yohimbe

Anatomical part for use

bark

Human use

Miscellaneous

Summary

Corynanthe johimbe, common name yohimbe, is a plant species in the family Rubiaceae native to western and central Africa (Nigeria, Cabinda, Cameroon, Congo-Brazzaville, Gabon, Equatorial Guinea). Extracts from yohimbe have been used in traditional medicine in West Africa as an aphrodisiac and have been marketed in developed countries as dietary supplements. (Source: Wiki)

Evidence Level

Level 0 (No convinced report of liver injury caused by herbal and dietary supplement)

Hepatotoxicity Description

In small clinical trials and case series, yohimbine therapy has not been linked to serum enzyme elevations or clinical liver disease. Although yohimbine is often found in weight loss and muscle building herbal combinations, it has not been associated with cases of clinically apparent acute liver injury. (Source: LiverTox)

Uses

The wood and bark are used for firewood and construction. Bark – the most commercially important product – is used in extractions to make tinctures for traditional medicine and dietary supplements.The main phytochemical in the extract is the indoloquinolizidine alkaloid yohimbine. It also contains other alkaloids, such as corynanthine and raubasine, with undefined properties, adding further to concerns about its safety. (Source: Wiki)

Human use and adverse effects

Extracts from yohimbe bark are used in West African traditional medicine in the belief that it is a herbal tonic and aphrodisiac. Yohimbe bark and extract are used in manufactured dietary supplements, but there is no scientific evidence they have any effect, and yohimbine levels may vary substantially among supplement products.Although proposed as a potential treatment for erectile dysfunction in humans, there are concerns about its safety or effectiveness. Side effects of using yohimbe, particularly in high doses, may include hypertension, increased heart rate, headache, nausea, tremors, and insomnia. Yohimbe bark extract has been declared as insufficiently characterized and possibly unsafe to consume by the European Union and US National Institutes of Health. Yohimbine specifically has so been declared by the European Union, but not by the US National Institutes of Health. (Source: Wiki)

Animal use

Yohimbine is used in veterinary medicine to reverse sedation in dogs, elk or deer. (Source: Wiki)